{"id":1325,"date":"2024-02-17T18:16:35","date_gmt":"2024-02-17T12:46:35","guid":{"rendered":"https:\/\/lotusarise.com\/qna\/?p=1325"},"modified":"2024-04-03T07:16:23","modified_gmt":"2024-04-03T01:46:23","slug":"q-consider-the-following-statements-46","status":"publish","type":"post","link":"https:\/\/lotusarise.com\/qna\/upsc\/q-consider-the-following-statements-46","title":{"rendered":"Q.\u00a0Consider the following statements:"},"content":{"rendered":"\n<ol class=\"wp-block-list\">\n<li>Genetic changes can be introduced in the cells that produce eggs or sperms of a prospective parent.<\/li>\n\n\n\n<li>A person\u2019s genome can be edited before birth at the early embryonic stage.<\/li>\n\n\n\n<li>Human induced pluripotent stem cells can be injected into the embryo of a pig.<\/li>\n<\/ol>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Which of the statements given above is\/are correct?<\/strong><\/p>\n\n\n\n<ul class=\"mcq wp-block-list\">\n<li>1 only<\/li>\n\n\n\n<li>2 and 3 only<\/li>\n\n\n\n<li>2 only<\/li>\n\n\n\n<li>1, 2 and 3<\/li>\n<\/ul>\n\n\n\n<blockquote class=\"wp-block-quote mcq is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\"><strong>Answer: (d) 1, 2 and 3<\/strong><\/p>\n<\/blockquote>\n\n\n\n<h5 class=\"wp-block-heading\" id=\"gene-therapy\">Gene Therapy<\/h5>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Gene therapy refers to the method wherein a&nbsp;<strong>genetic defect is treated by inserting a functional gene or section of DNA in cells.<\/strong>&nbsp;The&nbsp;<strong>functional gene inserted into an individual or an embryo compensates for the non-functional gene present.<\/strong>&nbsp;The newly inserted DNA corrects the effect of the mutated gene.<\/li>\n\n\n\n<li>On the basis of types of cells involved in the gene transfer, gene therapy is of two types:\n<ul class=\"wp-block-list\">\n<li><strong>Somatic gene therapy:&nbsp;<\/strong>Here the&nbsp;<strong>desired gene is transferred to a somatic cell<\/strong>. The gene is not transferred to the offspring.<\/li>\n\n\n\n<li><strong>Germline gene therapy:&nbsp;<\/strong>Here the&nbsp;<strong>desired gene is introduced in the germ cell.<\/strong>&nbsp;The gene gets transferred from one generation to another generation.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\n\n\n<h6 class=\"wp-block-heading\" id=\"germline-gene-therapy\">Germline gene therapy<\/h6>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Under this therapy,&nbsp;<strong>required DNA is transferred into the cells that produce reproductive cells, eggs or sperm, in the body.&nbsp;<\/strong><\/li>\n\n\n\n<li>It&nbsp;allows for the&nbsp;<strong>correction of disease-causing gene variants<\/strong>&nbsp;that are certain to be passed down from generation to generation.&nbsp;This therapy removes a hereditary disorder from a family line forever.<\/li>\n<\/ul>\n\n\n\n<h6 class=\"wp-block-heading\" id=\"somatic-cell-gene-therapy\">Somatic cell gene therapy<\/h6>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Somatic cell gene therapy is when&nbsp;<strong>therapeutic genes are transferred to a patient\u2019s somatic cells<\/strong>.<\/li>\n\n\n\n<li>The somatic gene therapy targets&nbsp;<strong>body tissues<\/strong>. These cells do not produce sperm or eggs, therefore the gene is not transferred to the next generation.<\/li>\n\n\n\n<li>Somatic cell gene therapy would&nbsp;<strong>aim to cure a disease only in the patient<\/strong>, not in the patient\u2019s descendants.<\/li>\n<\/ul>\n\n\n\n<h6 class=\"wp-block-heading\" id=\"humaninduced-pluripotent-stem-cells\">\u200b<strong>Human-induced pluripotent stem cells<\/strong><\/h6>\n\n\n\n<ul class=\"wp-block-list\">\n<li>They have been hailed as an effective replacement for human embryonic stem cells&nbsp;and a prime candidate cell source for regenerative medicine aims.<\/li>\n\n\n\n<li>The researchers tried combining human induced pluripotent stem cells with pig embryos.<\/li>\n\n\n\n<li>Many of the embryos were much smaller than normal and seemed to grow more slowly.&nbsp;<\/li>\n\n\n\n<li>Hence, so far there has not been a success in growing human organs in pigs.<\/li>\n\n\n\n<li><strong>But this experiment shows that human-induced pluripotent cells can be injected into pigs embryo.<\/strong><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Which of the statements given above is\/are correct? Answer: (d) 1, 2 and 3 Gene Therapy Germline gene therapy Somatic cell gene therapy \u200bHuman-induced pluripotent stem cells<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","footnotes":""},"categories":[1,3],"tags":[44],"years":[53],"class_list":["post-1325","post","type-post","status-publish","format-standard","hentry","category-upsc","category-prelims","tag-science-and-tech","years-53"],"acf":[],"taxonomy_info":{"category":[{"value":1,"label":"UPSC"},{"value":3,"label":"Prelims"}],"post_tag":[{"value":44,"label":"Science and Tech"}],"years":[{"value":53,"label":"2020"}]},"featured_image_src_large":false,"author_info":{"display_name":"LotusArise","author_link":"https:\/\/lotusarise.com\/qna\/author\/team-lotusarise"},"comment_info":0,"category_info":[{"term_id":1,"name":"UPSC","slug":"upsc","term_group":0,"term_taxonomy_id":1,"taxonomy":"category","description":"","parent":0,"count":1269,"filter":"raw","cat_ID":1,"category_count":1269,"category_description":"","cat_name":"UPSC","category_nicename":"upsc","category_parent":0},{"term_id":3,"name":"Prelims","slug":"prelims","term_group":0,"term_taxonomy_id":3,"taxonomy":"category","description":"","parent":1,"count":1251,"filter":"raw","cat_ID":3,"category_count":1251,"category_description":"","cat_name":"Prelims","category_nicename":"prelims","category_parent":1}],"tag_info":[{"term_id":44,"name":"Science and Tech","slug":"science-and-tech","term_group":0,"term_taxonomy_id":44,"taxonomy":"post_tag","description":"","parent":0,"count":167,"filter":"raw"}],"_links":{"self":[{"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/posts\/1325","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/comments?post=1325"}],"version-history":[{"count":1,"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/posts\/1325\/revisions"}],"predecessor-version":[{"id":1344,"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/posts\/1325\/revisions\/1344"}],"wp:attachment":[{"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/media?parent=1325"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/categories?post=1325"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/tags?post=1325"},{"taxonomy":"years","embeddable":true,"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/years?post=1325"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}