{"id":1296,"date":"2024-02-17T16:48:57","date_gmt":"2024-02-17T11:18:57","guid":{"rendered":"https:\/\/lotusarise.com\/qna\/?p=1296"},"modified":"2024-04-03T07:17:57","modified_gmt":"2024-04-03T01:47:57","slug":"q-the-term-ace2-is-talked-about-in-the-context-of","status":"publish","type":"post","link":"https:\/\/lotusarise.com\/qna\/upsc\/q-the-term-ace2-is-talked-about-in-the-context-of","title":{"rendered":"Q.\u00a0The term \u201cACE2\u201d is talked about in the context of"},"content":{"rendered":"\n<ul class=\"mcq wp-block-list\">\n<li>genes introduced in the genetically modified plants<\/li>\n\n\n\n<li>development of India\u2019s own satellite navigation system<\/li>\n\n\n\n<li>radio collars for wildlife tracking<\/li>\n\n\n\n<li>spread of viral diseases<\/li>\n<\/ul>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\"><strong>Answer: (d) spread of viral diseases<\/strong><\/p>\n<\/blockquote>\n\n\n\n<h5 class=\"wp-block-heading\" id=\"ace2\"><strong>ACE2<\/strong><\/h5>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Angiotensin-converting enzyme 2 is an enzyme attached to the membrane of cells in the intestines, kidney, testis, gallbladder, and heart.<\/strong><\/li>\n\n\n\n<li>The angiotensin-converting enzyme-2 (ACE-2) has been identified as the&nbsp;<strong>receptor for the SARS-CoV-2<\/strong>&nbsp;viral angiotensin-converting enzyme 2 (ACE2) acts as an entry point for coronavirus into the Human Body.<\/li>\n\n\n\n<li><strong>ACE2 is discussed in the context of the spread of viral disease.<\/strong><\/li>\n\n\n\n<li>ACE2 is a&nbsp;<strong>protein&nbsp;<\/strong>on the surface of many cell types. It is an enzyme that generates small proteins \u2013 by cutting up the larger protein angiotensinogen that then goes on to regulate functions in the cell.<\/li>\n\n\n\n<li>Using the spike-like protein on its surface, the SARS-CoV-2 virus binds to ACE2\u2013 like a key being inserted into a lock \u2013 before entry and infection of cells. Hence, ACE2 acts as a cellular doorway \u2013 a receptor\u2013 for the virus that causes COVID-19.&nbsp;&nbsp;<\/li>\n\n\n\n<li>SARS-CoV-2 uses a human enzyme called&nbsp;<strong>ACE2<\/strong>&nbsp;to enter into the cells of its host.<\/li>\n\n\n\n<li>ACE2 lowers&nbsp;<strong>blood pressure<\/strong>&nbsp;in the human body and works against another enzyme known as ACE (which has the opposite effect).<\/li>\n\n\n\n<li>The virus causes the levels of ACE to fall in the lungs and consequently pushes up the levels of ACE2.<\/li>\n\n\n\n<li>This happens as a chain reaction and increases the levels of the&nbsp;<strong>molecule bradykinin<\/strong>&nbsp;in the cells, causing a<strong>&nbsp;bradykinin storm.<\/strong><\/li>\n\n\n\n<li><strong>Bradykinin<\/strong>&nbsp;is a compound that is&nbsp;<strong>related to pain sensation and lowering blood pressure<\/strong>&nbsp;in the human body.<\/li>\n\n\n\n<li>Bradykinin storm causes the blood vessels to expand and become leaky, leading to swelling of the surrounding tissue.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Answer: (d) spread of viral diseases ACE2<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","footnotes":""},"categories":[1,3],"tags":[44],"years":[52],"class_list":["post-1296","post","type-post","status-publish","format-standard","hentry","category-upsc","category-prelims","tag-science-and-tech","years-52"],"acf":[],"taxonomy_info":{"category":[{"value":1,"label":"UPSC"},{"value":3,"label":"Prelims"}],"post_tag":[{"value":44,"label":"Science and Tech"}],"years":[{"value":52,"label":"2021"}]},"featured_image_src_large":false,"author_info":{"display_name":"LotusArise","author_link":"https:\/\/lotusarise.com\/qna\/author\/team-lotusarise"},"comment_info":0,"category_info":[{"term_id":1,"name":"UPSC","slug":"upsc","term_group":0,"term_taxonomy_id":1,"taxonomy":"category","description":"","parent":0,"count":1269,"filter":"raw","cat_ID":1,"category_count":1269,"category_description":"","cat_name":"UPSC","category_nicename":"upsc","category_parent":0},{"term_id":3,"name":"Prelims","slug":"prelims","term_group":0,"term_taxonomy_id":3,"taxonomy":"category","description":"","parent":1,"count":1251,"filter":"raw","cat_ID":3,"category_count":1251,"category_description":"","cat_name":"Prelims","category_nicename":"prelims","category_parent":1}],"tag_info":[{"term_id":44,"name":"Science and Tech","slug":"science-and-tech","term_group":0,"term_taxonomy_id":44,"taxonomy":"post_tag","description":"","parent":0,"count":167,"filter":"raw"}],"_links":{"self":[{"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/posts\/1296","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/comments?post=1296"}],"version-history":[{"count":1,"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/posts\/1296\/revisions"}],"predecessor-version":[{"id":1311,"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/posts\/1296\/revisions\/1311"}],"wp:attachment":[{"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/media?parent=1296"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/categories?post=1296"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/tags?post=1296"},{"taxonomy":"years","embeddable":true,"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/years?post=1296"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}