{"id":1269,"date":"2024-02-17T16:28:19","date_gmt":"2024-02-17T10:58:19","guid":{"rendered":"https:\/\/lotusarise.com\/qna\/?p=1269"},"modified":"2024-04-03T07:19:36","modified_gmt":"2024-04-03T01:49:36","slug":"q-in-the-context-of-vaccines-manufactured-to-prevent-covid-19-pandemic-consider-the-following-statements","status":"publish","type":"post","link":"https:\/\/lotusarise.com\/qna\/upsc\/q-in-the-context-of-vaccines-manufactured-to-prevent-covid-19-pandemic-consider-the-following-statements","title":{"rendered":"Q.\u00a0In the context of vaccines manufactured to prevent COVID-19 pandemic, consider the following statements:"},"content":{"rendered":"\n
    \n
  1. The Serum Institute of India produced COVID-19 vaccine named Covishield using<\/strong> mRNA<\/strong> platform.<\/li>\n\n\n\n
  2. Sputnik V vaccine is manufactured using vector based<\/strong> platform.<\/li>\n\n\n\n
  3. COVAXIN is an inactivated pathogen based<\/strong> vaccine.<\/li>\n<\/ol>\n\n\n\n

    Which of the statements given above are correct?<\/p>\n\n\n\n

      \n
    • 1 and 2 only<\/li>\n\n\n\n
    • 2 and 3 only<\/li>\n\n\n\n
    • 1 and 3 only<\/li>\n\n\n\n
    • 1, 2 and 3<\/li>\n<\/ul>\n\n\n\n
      \n

      Answer: (b) 2 and 3 only<\/strong><\/p>\n<\/blockquote>\n\n\n\n

      Covishield<\/strong><\/h5>\n\n\n\n
        \n
      • Covishield<\/strong> vaccine is based on the platform which uses a recombinant, replication-deficient chimpanzee adenovirus vector encoding<\/strong> the SARS-CoV-2 Spike (S) glycoprotein.<\/li>\n\n\n\n
      • The Serum Institute of India produced a COVID-19 vaccine named Covishield but not using mRNA platform.\n
          \n
        • It has been prepared using the viral vector platform<\/strong>. In the vaccine, a chimpanzee adenovirus \u2013 ChAdOx1 \u2013 has been modified to enable it to carry the COVID-19 spike protein into the cells of humans.<\/li>\n\n\n\n
        • This cold virus is basically incapable of infecting the receiver, but can very well teach the immune system to prepare a mechanism against such viruses.<\/li>\n\n\n\n
        • The same technology was used to prepare vaccines for viruses like Ebola.<\/li>\n<\/ul>\n<\/li>\n\n\n\n
        • On its administration, the genetic material of the part of coronavirus is expressed which generates an immune response.<\/li>\n\n\n\n
        • Covishield vaccine is developed by AstraZeneca and the University of Oxford. It is the Indian variant of AZD1222. Covishield vaccine is developed and manufactured by the Pune-based Serum Institute of India(SII) through a license from AstraZeneca and Oxford.<\/strong><\/li>\n\n\n\n
        • It is supposed that the immune system of the body will recognize this protein as a threat and work on building antibodies against it.<\/li>\n<\/ul>\n\n\n\n
          Sputnik V<\/strong><\/h5>\n\n\n\n
            \n
          • It is the world\u2019s first registered vaccine based on a well-studied human adenovirus vector platform<\/strong>.<\/li>\n\n\n\n
          • The Sputnik V vaccine has been developed by the Gamaleya National Research Institute of Epidemiology and Microbiology in Moscow.<\/strong><\/li>\n\n\n\n
          • It uses two different viruses that cause the common cold (adenovirus) in humans.<\/li>\n\n\n\n
          • The adenoviruses are weakened so they cannot replicate in humans and cannot cause disease.<\/li>\n\n\n\n
          • The gene from adenovirus, which causes the infection, is removed while a gene with the code of a protein from another virus spike is inserted.<\/li>\n<\/ul>\n\n\n\n
            Covaxin<\/strong><\/h5>\n\n\n\n
              \n
            • Covaxin is an inactivated viral vaccine<\/strong>.<\/li>\n\n\n\n
            • Covaxin vaccine, developed by Hyderabad-based Bharat Biotech<\/strong> in collaboration with the National Institute of Virology and uses a different platform.<\/li>\n\n\n\n
            • Covaxin is an \u201cinactivated\u201d <\/strong>vaccine that uses the killed SARS-CoV-2 virus and has no potential to infect or replicate once injected and just serves to uplift an immune response.<\/li>\n\n\n\n
            • They contain inactivated viruses, which cannot infect a person but still can teach the immune system to prepare a defence mechanism against the active virus. <\/strong><\/li>\n\n\n\n
            • It is developed with Whole-Virion Inactivated Vero Cell-derived technology.<\/li>\n\n\n\n
            • That is, it contains inactivated viruses that cannot infect a person, but still can teach the immune system to prepare a defence mechanism against the active virus.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"

              Which of the statements given above are correct? Answer: (b) 2 and 3 only Covishield Sputnik V Covaxin<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","footnotes":""},"categories":[1,3],"tags":[44],"years":[51],"class_list":["post-1269","post","type-post","status-publish","format-standard","hentry","category-upsc","category-prelims","tag-science-and-tech","years-51"],"acf":[],"taxonomy_info":{"category":[{"value":1,"label":"UPSC"},{"value":3,"label":"Prelims"}],"post_tag":[{"value":44,"label":"Science and Tech"}],"years":[{"value":51,"label":"2022"}]},"featured_image_src_large":false,"author_info":{"display_name":"LotusArise","author_link":"https:\/\/lotusarise.com\/qna\/author\/team-lotusarise"},"comment_info":0,"category_info":[{"term_id":1,"name":"UPSC","slug":"upsc","term_group":0,"term_taxonomy_id":1,"taxonomy":"category","description":"","parent":0,"count":1269,"filter":"raw","cat_ID":1,"category_count":1269,"category_description":"","cat_name":"UPSC","category_nicename":"upsc","category_parent":0},{"term_id":3,"name":"Prelims","slug":"prelims","term_group":0,"term_taxonomy_id":3,"taxonomy":"category","description":"","parent":1,"count":1251,"filter":"raw","cat_ID":3,"category_count":1251,"category_description":"","cat_name":"Prelims","category_nicename":"prelims","category_parent":1}],"tag_info":[{"term_id":44,"name":"Science and Tech","slug":"science-and-tech","term_group":0,"term_taxonomy_id":44,"taxonomy":"post_tag","description":"","parent":0,"count":167,"filter":"raw"}],"_links":{"self":[{"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/posts\/1269","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/comments?post=1269"}],"version-history":[{"count":1,"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/posts\/1269\/revisions"}],"predecessor-version":[{"id":1288,"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/posts\/1269\/revisions\/1288"}],"wp:attachment":[{"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/media?parent=1269"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/categories?post=1269"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/tags?post=1269"},{"taxonomy":"years","embeddable":true,"href":"https:\/\/lotusarise.com\/qna\/wp-json\/wp\/v2\/years?post=1269"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}